16 February 2022

Memo Therapeutics AG Closes Series B Financing at CHF37 Million Following Oversubscribed CHF23 Million Extension

Proceeds will be used to advance antibody against BK virus through Phase 2 clinical development

Memo Therapeutics AG (“MTx”), an innovator in the field of antibody discovery and development, announced today the close of an oversubscribed Series B financing round led by Swisscanto Invest at CHF37 million after securing an additional CHF23 million from a combination of strategic and financial investors, including Adjuvant Capital, Fresenius Medical Care Ventures, GF Group, Verve Ventures, Vesalius Biocapital and Zürcher Kantonalbank.

The proceeds will be used to advance clinical development of its best- and first-in-class neutralizing antibody, MTX-005, targeting BK virus infection in renal transplant patients through Phase 2 clinical development. BK virus infection poses a high and unmet medical need to transplant success and presents a large (more than USD1 billion) and growing market (more than 15% p.a.) opportunity. In addition, MTx will use the funding to develop and expand its antibody pipeline and secure new partnering agreements.

“We are extremely impressed with the power of Memo Therapeutics AG’s antibody technologies, which provide best-in-class B-cell repertoire coverage from any donor species and single-cell-based high-throughput functional screening capabilities, which enable direct analysis of millions of candidate antibodies,” said Dr. Andreas Wüpper, Director of Investments at Fresenius Medical Care Ventures. “We believe this approach is applicable to many therapeutic areas and look forward to seeing the results from clinical evaluation of the BK virus program.”

“Our unique approach to discover and develop novel therapeutic antibodies continues to generate impressive data. This progress has resonated with highly renowned strategic and financial investors, who we are happy to welcome in this oversubscribed extension of our Series B,” said Dr. Karsten Fischer, Chief Executive Officer of Memo Therapeutics AG. “This funding, together with the recent Swiss Federal government COVID-19 grant, will enable us to advance our two lead programs, MTX-005 and COVAB 36, into clinical development this year and to develop and expand our antibody pipeline, which includes cytomegalovirus (CMV) and Nipah virus.”

As part of the financing round, Dr. Andreas Wüpper, Director of Investments at Fresenius Medical Care Ventures, Dr. Christian Schneider, Managing Partner at Vesalius Biocapital and Dr. Philippe Dro, Partner at Adjuvant Capital will join the MTx Board of Directors.

MTx recently announced that it has received a CHF10.5 million commitment from the Swiss Federal Funding Programme for COVID-19 Medicines to advance COVAB 36, a potent, fully human monoclonal antibody administered via inhalation for the treatment of SARS-CoV-2 infections, into clinical development.

About Memo Therapeutics AG

Memo Therapeutics AG is an innovator in the field of antibody discovery and immune repertoire analysis. The company’s antibody discovery platform uses robust, simple, and fast microfluidic single-cell molecular cloning and screening technologies to enable antibody repertoire mining and antibody discovery at unprecedented speed, efficiency, and sensitivity.

The platform captures and preserves entire B-cell repertoires from any donor species and any B-cell type in recombinant form for display using mammalian cells. The antibody repertoires are subsequently screened in single-cell format using microfluidic screening technology that can assess millions of candidate antibodies directly in functional assays, resulting in recombinant clonal cell lines expressing monoclonal antibodies (mAbs) with the desired functional properties.

Exploiting the power of its microfluidic single-cell molecular cloning and screening technologies, Memo Therapeutics AG engages in antibody discovery across species and indications for proprietary and partnered projects. The company’s current pipeline features programs in infectious diseases and immuno-oncology. Memo Therapeutics AG is a private company located in Bio-Technopark Zurich, Switzerland.